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With a newly-obtained fiery red blood meal visible through her transparent abdomen, the now heavy female Aedes aegypti mosquito takes flight. Clostridium botulinum growing on egg yolk agar showing the lipase reaction.An atypical enlarged lymphocyte found in the blood smear from a HPS patient. (a) An atypical enlarged lymphocyte found in the blood smear from a HPS patient. (b)Burkholderia psudeomallei grown on sheep blood agar for 24 hours.

Research


Dengue

Secreted NS1 and anti-NS1 antibody in dengue pathogenesis
Eva Harris, UC Berkeley
 
Transcriptional profile of the host response to dengue fever
David Relman, Stanford University
 
Detection and discovery of viruses associated with dengue-like illness
Joseph DeRisi, UC San Francisco
 
Genetic signatures of dengue virus emergence
Shannon Bennett, University of Hawaii
 
Mosquito innate immune responses to dengue virus
Anthony James, UC Irvine
 
Flavivirus RNA replication proteins as novel targets for drug discovery
Bert Semler, UC Irvine (DP)
 
Structure and function of dengue protease
Peter Kuhn, The Scripps Research Institute (DP)

 

Viral Zoonoses


Antivirals and vaccines against arenavirus infections
Michael Buchmeier, UC Irvine
 
Targeting the entry pathway of New World arenaviruses
Paula Cannon, USC
 
Nipah and Hendra virus entry and budding
Behnur Lee, UC Los Angeles
 
Novel approaches for the development of live attenuated viral vaccines
David Clark, UC Davis/Aaron Brault, Centers for Disease Control

 

Botulinum Neurotoxin


Structural diversity of botulinum neurotoxins
Raymond Stevens. The Scripps Research Institute
 
Evolving diagnostic antibodies for botulinum neurotoxins
James Marks, UC San Francisco
 
Highly-sensitive in vitro assay for botulinum neurotoxins
Markus Kalkum, City of Hope
 
Benchtop device for botulinum neurotoxins
Dobrin Nedelkov, Intrinsic Bioprobes, Inc.

 

Burkholderia


Burkholderia pseudomallei autotransporter and TPS proteins
Peggy Cotter, UC Santa Barbara
 
Type III secretion in Burkholderia pseudomallei
Jeff F. Miller, UC Los Angeles
 
Genomic correlates of virulence in experimental melioidosis
Paul Keim, Northern Arizona University
 
Antigenemia immunoassay for diagnosis melioidosis
Thomas Kozel, Ph.D.
 
Regulatory networks controlling virulence in B. pseudomallei
Imke Schroeder, UC Los Angeles (DP)

 

Bacterial Zoonoses


Intracellular biology of F. tularensis
Marcus Horwitz, UC Los Angeles
 
Molecular mechanisms of F. tularensis pathogenesis and immunity
Denise Monack, Stanford University
 
Infection and immunity in reservoir hosts
Alan Barbour, UC Irvine
 
Development of poxvirus-based vectors as reservoir vaccines
Bertram Jacobs, Arizona State University (DP)
 
Environmental amoebas and F. tularensis
Amy Rasley, Lawrence Livermore National Laboratory (DP)
 
Virulence of diverse Yersinia pestis strains in animals
David Wagner, Northern Arizona University (CDA)

 

Coccidioidomycosis


Coccidioides proteins as vaccines and diagnostics
John Galgiani, University of Arizona
 
Comparative genomics to identify Coccidioides virulence factors
Anita Sil, UC San Francisco/John Taylor, UC Berkeley

 

 


 

 

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